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Adhesion Molecules Expression. Beta 1 Integrin and ICAM-1 as Potential Markers of Cutaneous Radiation Injuries Induced by Ionizing Radiation Overexposures

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Etiquetas

  • radiaciones ionizantes
  • proteccion contra las radiaciones
  • moleculas
  • arn argentina
  • lesiones
  • adhesion

Datos

Origen

Argentina

Idioma

Español

Organización

ARN (Argentina)

Autor

Lendoiro, N.; de la Vega, A.; Portas, M.; Dubner, D.; Rossini, A

Previsualización

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Descripción

During the inflammatory response, there is a process of leukocyte extravasation that involves the migration of these cells from the bloodstream towards target tissues. Cell adhesion molecules (CAMs) mediate interactions between blood cells and endothelial cells as a response to inflammation under certain conditions such as overexposure to ionizing radiation. On the other hand, the beta integrin family of proteins interacts with the associated ligand (intercellular adhesion molecules) in the vascular endothelium. This transient binding results in further leukocyte activation and subsequent firm adhesion and transendothelial migration into sites of inflammation. 15th International Congress of the International Radiation Protection Association. Seoul, Korea, 18 al 19 de enero de 2021